Characterization of Interstitial Cajal Progenitors Cells and Their Changes in Hirschsprung’s Disease

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Characterization of Interstitial Cajal Progenitors Cells and Their Changes in Hirschsprung’s Disease

Interstitial cells of Cajal (ICC) are critical to gastrointestinal motility. The phenotypes of ICC progenitors have been observed in the mouse gut, but whether they exist in the human colon and what abnormal changes in their quantity and ultrastructure are present in Hirschsprung's disease (HSCR) colon remains uncertain. In this study, we collected the surgical resection of colons, both proxima...

متن کامل

Gastrointestinal Stromal Tumors, Interstitial Cells of Cajal and their Nomenclature

Currently, gastrointestinal stromal tumors (GIST) have been emphasized considerably in the literature. Following the date of the description of interstitial cells of Cajal (ICC) by Santiago Ramon y Cajal in the late 19th century, this issue has been very popular. Lately, discovery of the association of GISTs with c-Kit mutations in their development, and the significance of drugs such as imatin...

متن کامل

Interstitial cells of Cajal in enteric neurotransmission.

Specialised cells known as interstitial cells of Cajal (ICCs), distributed in specific locations within the tunica muscularis of the gastrointestinal tract, serve as electrical pacemakers and mediators of enteric neurotransmission. Until recently, evidence to support a functional role of these cells has been, for the most part, indirect. The role of ICCs in pacemaking or neurotransmission has b...

متن کامل

Interstitial cells of Cajal in the urethra

The smooth muscle layer of the urethra generates spontaneous myogenic tone that is thought to make a major contribution to urinary continence. The mechanisms underlying generation of tone remain unclear, however recent studies from our laboratory highlighted a role for a specialised population of pacemaker cells which we originally referred to as interstitial cells (IC) and now term ICC. Urethr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: PLoS ONE

سال: 2014

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0086100